Studies on the Antitubercular Compounds (XII) Effect on Antitubercular Activity of Acid Hydrazide by the Condensation with Aldehyde Shichiro
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Design and Synthesis of Some Novel Fluorobenzimidazoles Substituted with Structural Motifs Present in Physiologically Active Natural Products for Antitubercular Activity
Keeping in view the drawbacks associated with research on anti-TB drugs based on plant extracts and the non-availability of fluorinated natural products with antitubercular activity has prompted us to make an effort towards the synthesis and characterization of a novel series of fifteen substituted fluorobenzimidazoles. The newly synthesized compounds were characterized by I.R, 1H-NMR, 13C-NMR,...
متن کاملDesign and Synthesis of Some Novel Fluorobenzimidazoles Substituted with Structural Motifs Present in Physiologically Active Natural Products for Antitubercular Activity
Keeping in view the drawbacks associated with research on anti-TB drugs based on plant extracts and the non-availability of fluorinated natural products with antitubercular activity has prompted us to make an effort towards the synthesis and characterization of a novel series of fifteen substituted fluorobenzimidazoles. The newly synthesized compounds were characterized by I.R, 1H-NMR, 13C-NMR,...
متن کاملAntitubercular Activity and Isolation of Chemical Constituents from plant Vitex negundo Linn.
Tuberculosis still remains a leading cause of death in the world. Currently considerable interest in natural products and their derivatives in the area of drug research for multidrug resistant tuberculosis (MDR-TB). The present investigation focused on identification, isolation, characterization of lead constituents and to determine the antitubercular activity of their enriched fractions and is...
متن کاملAntitubercular Activity and Isolation of Chemical Constituents from plant Vitex negundo Linn.
Tuberculosis still remains a leading cause of death in the world. Currently considerable interest in natural products and their derivatives in the area of drug research for multidrug resistant tuberculosis (MDR-TB). The present investigation focused on identification, isolation, characterization of lead constituents and to determine the antitubercular activity of their enriched fractions and is...
متن کاملIn vitro Antitubercular activity of novel 3-(4- Methoxyphenyl)-1-isonicotinoyl-5-(substituted phenyl)- formazans
In the present investigation, a series of 3-(4-methoxyphenyl)-1-isonicotinoyl-5-(substituted phenyl)-formazans (5a-r) were synthesized by condensation of schiff base (3) and diazonium salt of various substituted aromatic amines, (3a-r). The intermediate schiff base (3) was itself synthesized by condensation of isonicotinic acid hydrazide with 4methoxybenzaldehyde (2). The structures of the comp...
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تاریخ انتشار 2017